| Sporting CP til 1/8-finaler | |
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| 16.02.2023 | Sporting CP - FC Midtjylland 1-1 | | 23.02.2023 | FC Midtjylland - Sporting CP 0-4 |
| 77. | 0-1 | Emam Ashour | | 21. | 0-1 | Sebastián Coates |
| 90. | 1-1 | Sebastián Coates | | 38. |  | Paulinho, FC Midtjylland |
| | | | | 50. | 0-2 | Pedro Goncalves |
| | | | | 77. | 0-3 | Pedro Goncalves |
| | | | | 85. | 0-4 | Selvmål, Stefan Gartenmann |
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| 16.02.2023 | FC Salzburg - Roma 1-0 | | 23.02.2023 | Roma - FC Salzburg 2-0 |
| 88. | 1-0 | Nicolas Capaldo | | 33. | 1-0 | Andrea Belotti |
| | | | | 40. | 2-0 | Paulo Dybala |
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| Shakhtar Donetsk til 1/8-finaler (vandt 5-4 på straffe) | |
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| 16.02.2023 | Shakhtar Donetsk - Rennes 2-1 | | 23.02.2023 | Rennes - Shakhtar Donetsk 2-1 |
| 11. | 1-0 | Dmytro Kryskiv | | 52. | 1-0 | Karl Toko Ekambi |
| 45. | 2-0 | Artem Bondarenko, straffe | | 106. | 2-0 | Ibrahim Salah |
| 59. | 2-1 | Karl Toko Ekambi | | 119. | 2-1 | Selvmål, Jeanuël Belocian |
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| Union Berlin til 1/8-finaler | |
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| 16.02.2023 | Ajax - Union Berlin 0-0 | | 23.02.2023 | Union Berlin - Ajax 3-1 |
| | | | | 20. | 1-0 | Robin Knoche, straffe |
| | | | | 44. | 2-0 | Josip Juranovic |
| | | | | 47. | 2-1 | Mohammed Kudus |
| | | | | 50. | 3-1 | Danilho Doekhi |
| | | | | 90. | | Edson Álvarez, Ajax |
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| Leverkusen til 1/8-finaler (vandt 5-3 på straffe) | |
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| 16.02.2023 | Leverkusen - Monaco 2-3 | | 23.02.2023 | Monaco - Leverkusen 2-3 |
| 9. | 0-1 | Selvmål, Lukas Hradecky | | 13. | 0-1 | Florian Wirtz |
| 48. | 1-1 | Moussa Diaby | | 19. | 1-1 | Wissam Ben Yedder, straffe |
| 59. | 2-1 | Florian Wirtz | | 21. | 1-2 | Exequiel Palacios |
| 74. | 2-2 | Krepin diatta | | 58. | 1-3 | Amine Adli |
| 90. | 2-3 | Axel Disasi | | 84. | 2-3 | Breel Embolo |
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| 16.02.2023 | Sevilla - PSV Eindhoven 3-0 | | 23.02.2023 | PSV Eindhoven - Sevilla 2-0 |
| 45. | 1-0 | Youssef En-Nesyri | | 77. | 1-0 | Luuk de Jong |
| 50. | 2-0 | Lucas Ocampos | | 90. | 2-0 | Fabio Silva |
| 55. | 3-0 | Nemanja Gudelj | | | | |
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| Manchester United til 1/8-finaler | |
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| 16.02.2023 | FC Barcelona - Manchester United 2-2 | | 23.02.2023 | Manchester United - FC Barcelona 2-1 |
| 50. | 1-0 | Marcos Alonso | | 18. | 0-1 | Robert Lewandowski, straffe |
| 53. | 1-1 | Marcus Rashford | | 47. | 1-1 | Fred |
| 59. | 1-2 | Selvmål, Jules Koundé | | 73. | 2-1 | Antony |
| 76. | 2-2 | Raphinha | | | | |
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| 16.02.2023 | Juventus - Nantes 1-1 | | 23.02.2023 | Nantes - Juventus 0-3 |
| 13. | 1-0 | Dusan Vlahovic | | 5. | 0-1 | Angel Di Maria |
| 60. | 1-1 | Ludovic Blas | | 17. |  | Nicolas Pallois, Nantes |
| | | | | 20. | 0-2 | Angel Di Maria, straffe |
| | | | | 78. | 0-3 | Angel Di Maria |
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Forside