| 13.04.2022 (18:30): RANDERS FC - FC MIDTJYLLAND | |
| | 17. | 0-1 | Charles | Morten Krogh | | | 45. | 0-2 | Henrik Dalsgaard | | | | 82. | 0-3 | Anders Dreyer | | | | 90. | 1-3 | Tosin Kehinde | | | |
| | Patrik Carlgren | David Ousted | | | Björn Kopplin  (77) | Henrik Dalsgaard  (45) | | | Simon Piesinger | Daniel Høegh | | | Hugo Andersson  (84) | Mads Døhr Thychosen (84) | | | Oliver Bundgaard (46) | Joel Andersson | | | Tosin Kehinde (90) | Charles (17) | | | Frederik Lauenborg (75) | Evander Ferreira | | | Lasse Berg Johnsen | Paulinho (70) | | | Simon Tibbling (46) | Anders Dreyer (82) / (84) | | | Vito Hammershøy-Mistrati (84) | Junior Brumado (61) | | | Stephen Odey | Gustav Isaksen (70) | | |
| | | Mikkel Kallesøe  (46) | Max Meier (70) | | | Jakob Ankersen (46) | Edward Chilufya (61) | | | Mads Enggård (84) | Vagner Love (84) | | | Jesper Lauridsen (84) | Erik Sviatchenko (84) | | | Tobias Klysner | Jared Thompson | | | Jonas Dakir | Marrony | | | Filip Bundgaard (75) | Nikolas Dyhr (70) | | | |
| 14.04.2022 (16:00): SILKEBORG - FC KØBENHAVN | |
| | 59. | 1-0 | Nicolai Vallys | Anders Poulsen | | | 74. | 2-0 | Nicklas Helenius | | | | 89. | 2-1 | Hakon Arnar Haraldsson | | | | 90. | 3-1 | Søren Tengstedt | | | |
| | Nicolai Larsen | Kamil Grabara | | | Rasmus Carstensen | Peter Ankersen | | | Tobias Salquist | Denis Vavro (84) | | | Joel Felix | David Khocholava (79) | | | Lukas Engel | Kevin Diks (67) | | | Stefan Teitur Thordarson (67) | Rasmus Falk | | | Mark Brink (81) | Lukas Lerager (79) | | | Anders Klynge (90) | Hakon Arnar Haraldsson (89) | | | Sebastian Jørgensen (81) | Paul Mukairu (56) | | | Nicolai Vallys (59) | Pep Biel | | | Nicklas Helenius (74) | Victor Claesson (79) | | |
| | | Oliver Sonne | Isak Bergmann Johannesson (79) | | | Pelle Mattsson (81) | Khouma Babacar (79) | | | Søren Tengstedt (81) / (90) | Nicolai Boilesen (79) | | | Stan van Bladeren | Karl-Johan Johnsson | | | Robert Gojani (67) | William Bøving | | | Andreas Oggesen (90) | Victor Kristiansen (67) | | | Alexander Busch | Roony Bardaghji (56) | | | |
| 14.04.2022 (18:00): BRØNDBY - AAB | |
| | 33. | 0-1 | Louka Prip, straffe | Mikkel Redder | | |
| | Mads Hermansen | Jacob Rinne | | | Andreas Bruus | Mathias Ross | | | Sigurd Rosted (71) / (82) | Rasmus Thelander | | | Andreas Maxsø | Daniel Granli | | | Blas Riveros | Kristoffer Pallesen (41) | | | Joe Bell | Malthe Højholt (25) | | | Anis Ben Slimane | Iver Fossum | | | Christian Cappis (74) | Jakob Ahlmann (80) / (80) | | | Simon Hedlund | Kasper Kusk (58) | | | Mathias Kvistgaarden (68) | Louka Prip (33) | | | Marko Divkovic | Milan Makaric (58) | | |
| | | Mathias Greve (74) | Lucas Andersen (58) | | | Andrija Pavlovic (68) | Anders Hagelskjær (41) | | | Carl Björk | Anosike Ementa | | | Thomas Mikkelsen | Casper Gedsted (80) | | | Kevin Tshiembe | Oliver Ross | | | Frederik Ibsen (82) | Kasper Høgh (58) | | | Mads Hermansen | Theo Sander | | | |
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