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| | Milan - Ferencvaros .....0-2 | | | | Hapoel Beer-Sheva - OFI Kreta ..... 0-2 | |
| | Real Sociedad - Lyon .....1-1 | | | | Torreense - Ararat-Armenia ..... 3-2 | |
| | Sparta Prag - Bournemouth .....1-3 | | | | Celta Vigo - Union SG ..... 1-2 | |
| | Leverkusen - Marseille ..... 0-1 | | | | Sunderland - Dinamo Zagreb ..... 0-2 | |
| | Anderlecht - FC Salzburg .....2-0 | | | | Sturm Graz - NK Celje ..... 2-3 | |
| | Crystal Palace - Hoffenheim .....1-1 | | | | Celtic - Besiktas ..... 3-2 | |
| | Nijmegen - Omonia Nicosia .....3-1 | | | | AZ - Juventus ..... 1-2 | |
| | Lillestrøm - Viktoria Plzen .....0-1 | | | | Benfica - Lech Poznan ..... 3-1 | |
| | Levski Sofia - Jagiellonia Bialystok .....1-0 | | | | | |
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| | FC København - Iberia 1999 .....2-1 | | | | AGF - Sporting Braga ..... 0-0 | |
| | Monaco - FC Nordsjælland .....2-0 | | | | FC Midtjylland - Ajax ..... 1-6 | |
| | Riga FC - FK Jablonec .....1-1 | | | | Atalanta - FC Kairat ..... 1-1 | |
| | Universitatea Craiova - Egnatia .....2-0 | | | | Røde Stjerne Beograd - Inter Club d'Escaldes ..... 2-1 | |
| | St. Truiden - Brann .....1-1 | | | | Kuopio PS - Gent ..... 0-0 | |
| | Twente - Pafos FC .....3-1 | | | | Lincoln Red Imps - Hajduk Split ..... 1-0 | |
| | Getafe - Brighton .....0-1 | | | | Trabzonspor - Freiburg ..... 0-1 | |
| | FC Lugano - Kauno Zalgiris .....3-0 | | | | FC Thun - Hearts ..... 3-1 | |
| | Panathinaikos - CSKA Sofia .....2-1 | | | | Mjällby - Borac Banja Luka ..... 2-0 | |
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| | Shakhtar Donetsk - Sporting CP .....0-1 | | | | Feyenoord - Inter ..... 0-3 | |
| | Galatasaray - Stuttgart .....0-2 | | | | Bodø/Glimt - Lille ..... 0-0 | |
| | FC Barcelona - Aston Villa .....3-0 | | | | Villarreal - Paris SG ..... 0-6 | |
| | Atletico Madrid - Bayern München .....0-2 | | | | LASK Linz - Slovan Bratislava ..... 4-0 | |
| | Manchester United - Roma .....3-2 | | | | | |
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| | Juventus - Rennes .....2-2 | | | | Lillestrøm - Real Sociedad ..... 0-6 | |
| | Ferencvaros - Torreense .....4-1 | | | | Besikta Crystal Palace ..... 2-2 | |
| | Union SG - Hapoel Beer-Sheva .....4-0 | | | | Hoffenheim - Lyon ..... 3-0 | |
| | Dinamo Zagreb - Nijmegen .....2-4 | | | | Omonia Nicosia - Benfica ..... 1-4 | |
| | Sturm Graz - Marseille .....1-0 | | | | Jagiellonia Bialystok - Anderlecht ..... 0-3 | |
| | Lech Poznan - Sunderland .....1-1 | | | | NK Celje - FC Salzburg ..... 2-2 | |
| | OFI Kreta - Leverkusen .....0-2 | | | | Bournemouth - Milan ..... 3-0 | |
| | Ararat-Armenia - AZ .....0-4 | | | | Celtic - Celta Vigo ..... 1-2 | |
| | Olympiakos Piræus - Sparta Prag .....1-0 | | | | Viktoria Plzen - Levski Sofia ..... 1-2 | |
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| | AGF - Egnatia .....1-1 | | | | FC Nordsjælland - CSKA Sofia ..... 2-2 | |
| | FC Midtjylland - St. Truiden .....0-1 | | | | Røde Stjerne Beograd - FC København ..... 2-2 | |
| | Lincoln Red Imps - Twente .....1-4 | | | | Inter Club d'Escaldes - Universitatea Criova ..... 1-3 | |
| | Iberia 1999 - Mjällby .....1-1 | | | | Kauno Zalgiris - Brann ..... 1-4 | |
| | Sporting Braga - Gent .....2-0 | | | | Getafe - FC Lugano ..... 2-5 | |
| | Ajax - Atalanta .....2-0 | | | | Trabzonspor - Hearts ..... 2-0 | |
| | Monaco - Freiburg .....3-0 | | | | FK Jablonec - Brighton ..... 0-0 | |
| | FC Thun - Hajduk Split .....0-1 | | | | FC Kairat - Panathinaikos ..... 1-5 | |
| | Borac Banja Luka - Kuopio PS .....2-0 | | | | Pafos FC - Riga FC ..... 1-1 | |
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| | Sporting CP - LASK Linz ..... 2-3 | | | | Como - Manchester United ..... 4-1 | |
| | Aston Villa - Viking ..... 3-1 | | | | Bayern München - Arsenal ..... 2-2 | |
| | Club Brugge - Lens ..... 3-0 | | | | Real Madid - RB Leipzig ..... 4-1 | |
| | Real Betis - Feyenoord ..... 1-0 | | | | Inter - Shakhtar Donetsk ..... 1-0 | |
| | Lille - Galatasaray ..... 2-4 | | | | | |
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